Posts Tagged ‘Source’

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Saturday, March 17th, 2012

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Thursday, March 15th, 2012

Showcasing Austin?s haughty institution of circus the Star of Texas Fair and Rodeo has been surrounded subsistence since 1938. Originally known as the Travis County Baby Beef Show plus held equitable inverse the Texas state chief building,asics gels, the circus has grown from these humble beginnings to encompass virtually a month?s worth of events each daily The Travis County Expo Center was originally established in 1983 specifically to house the Star of Texas Rodeo plus provides a total venue as the event?s mandate of rodeo-themed events and museums.
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BrocktonPost Sports & Recreation: Softball signups ? ? Posterous …

Monday, February 20th, 2012

BrocktonPost Sports & Recreation: Softball signups ? ? Posterous

Posted by on February 19, 2012 , No comment

BrocktonPost
BROCKTON?Brockton Youth Softball League for Girls will host 2012 spring registrations March 1 and March 2 at the Raymond Elementary School, 125 Oak St., from 6 to 8 p.m.
For on line registration or more information check out BYSL?s website at www.brocktonyouthsoftball.net/
For other information call 508-941-5766.

Source: http://brocktonsports.blogspot.com/2012/02/softball-signups.html

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Friday, December 9th, 2011

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Potential new drug target in Lou Gehrig’s disease

Tuesday, November 15th, 2011

ScienceDaily (Nov. 14, 2011) ? Two proteins conspire to promote a lethal neurological disease, according to a study published online this week in the Journal of Experimental Medicine.

Amyotrophic lateral sclerosis (ALS), also known as Lou Gehrig’s disease, is a devastating neurodegenerative disorder that results in progressive loss of motor function and ultimately death. More than 90% of ALS cases have no known genetic cause or family history. However, in some patients, spinal cord cells contain unusual accumulations of a protein called TDP-43.

Jean-Pierre Julien and colleagues at Laval University in Quebec now find that TDP-43 binds to an inflammatory protein called NF-kB p65 in the spinal cords of ALS patients but not of healthy individuals. TDP-43 and p65 were also more abundant in ALS than healthy spinal cords. In spinal cord cells called microglia, TDP-43 and p65 cooperated to ramp up production of factors capable of promoting inflammation and killing nearby neurons. In a mouse model of ALS, treatment with an agent capable of blocking p65 activity minimized neuron loss and eased disease symptoms.

These findings highlight p65 as a potential therapeutic target for this debilitating disorder.

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The above story is reprinted from materials provided by Rockefeller University Press, via Newswise.

Note: Materials may be edited for content and length. For further information, please contact the source cited above.


Journal Reference:

  1. Vivek Swarup, Daniel Phaneuf, Nicolas Dupr?, Susanne Petri, Michael Strong, Jasna Kriz, and Jean-Pierre Julien. Deregulation of TDP-43 in amyotrophic lateral sclerosis triggers nuclear factor ?B?mediated pathogenic pathways. Journal of Experimental Medicine, 2011 DOI: 10.1084/jem.20111313

Note: If no author is given, the source is cited instead.

Disclaimer: This article is not intended to provide medical advice, diagnosis or treatment. Views expressed here do not necessarily reflect those of ScienceDaily or its staff.

Source: http://www.sciencedaily.com/releases/2011/11/111114133630.htm

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AP Source: LSU suspends Mathieu, Simon, Ware (AP)

Friday, October 21st, 2011

BATON ROUGE, La. ? A person familiar with the decision says No. 1 LSU has suspended star cornerback Tyrann Mathieu, defensive back Tharold Simon and running back Spencer Ware for this Saturday’s home game against Auburn because they’ve run afoul of the team’s drug policy.

The person told The Associated Press about the suspensions on Wednesday on condition of anonymity because they have not been announced. LSU coach Les Miles declined to confirm any punishment for the three players, saying only that he is dealing with an internal disciplinary matter.

Mathieu has forced four fumbles, recovering three and returning two for scores. He also has two interceptions and 42 tackles, including 1 1/2 sacks.

Ware is unbeaten LSU’s leading rusher with 512 yards and six touchdowns.

Simon has one interception and 29 tackles.

Source: http://us.rd.yahoo.com/dailynews/rss/sports/*http%3A//news.yahoo.com/s/ap/20111020/ap_on_sp_co_ne/fbc_lsu_suspensions

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Friday, June 24th, 2011

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